News Archive

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For United States customers: New regulations for importing Drosophila (May 3, 2021)
VDRC stockcenter offline on Tuesday, 27.04.2021, 6pm-6:30pm CET (Apr 27, 2021)
End of year ordering/shipping schedule (Nov 17, 2020)
Update regarding VDRC shipping operations (May 10, 2020)
Shipping operations resumed (Apr 07, 2020)
COVID-19 emergency update (Mar 13, 2020)
Shipping update regarding coronavirus (Feb 28, 2020)
Sub-library lists of RNAi lines (GD, KK, shRNA) (Dec 02, 2020)
End of year ordering/shipping schedule (Nov 11, 2019)
New lines added - Heidelberg CFD CRISPR library (Sep 04, 2019)
New price scheme - as of 4th September 2019 (Sep 04, 2019)
Stock Pruning List, RNAi lines (GD and KK libraries) - order by 15th Sep 2019 (Aug 15, 2019)
Stock Pruning List, VT GAL4 - order by Sep 30th 2019 (Aug 07, 2019)
General price increase (Dec 20, 2018)
End of year ordering/shipping schedule (Nov 5, 2018)
New stocks added from Ameres lab (Mar 06, 2018)
Import regulation for US and Canada (Dec 22, 2017)
End of year ordering/shipping schedule (Nov 2, 2017)
Further shRNA lines available (Sep 18, 2017)
25th European Drosophila Research Conference in London, Sep 22-25, 2017 (Sep 17, 2017)
Vienna Tiles (VT) GAL4 Stock Pruning List - order by 30th Sep 2017 (Jul 11, 2017)
57th Annual Drosophila Research Conference in San Diego, March 29 - April 2, 2017 (Mar 20, 2017)
"NEW" and "SIMILAR" tags added in search results (Jan 25, 2017)
VDRC website relaunch (Dec 15, 2016)
End of year shipping schedules (Nov 10, 2016)
VDRC stockcenter offline 14.10.2016 to 17.10.2016 (Oct 11, 2016)
Potential payment problems (June 22, 2016)
New stocks added from Wasser lab (May 18, 2016)
New stocks added from Harvey lab (May 11, 2016)
RNAi collection extended – new shRNA lines added (Apr. 18, 2016)
New stocks added from Brennecke group (Feb. 18, 2016)
KK landing site update (Jan. 14, 2016)
VDRC host institute name change (Jan. 01, 2016)

Older news entries can be requested by contacting office@vdrc.at.

For United States customers: New regulations for importing Drosophila (May 3, 2021)

New documents and practices for importing Drosophila into the United States were implemented by the USDA as of April 5th 2021.
To receive your imported packages from the VDRC, you will need a "Letter of No Permit Required” (LONPR).
For information on how to obtain this document see VDRC shipping information.

The LONPR document greatly simplifies the import procedure since it:

  • may be used for an unlimited number of shipments,
  • may be used to import strains from any country,
  • has no expiration date.

Shipping via the old documents (Courtesy Permit and a "Letter of No Jurisdiction") will still be valid until the permit expiry date, but we recommend that you obtain a new “Letter of No Permit Required” as soon as possible.

We thank the BDSC and USDA for greatly simplifying the import procedures for the Drosophila research community!

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VDRC stockcenter offline on Tuesday, 27.04.2021, 6pm-6:30pm CET (Apr 27, 2021)

Dear VDRC users,

Due to a maintenance in our central server infrastructure, placing orders may not be possible on 27th April 2021 between 6pm and 6:30pm (CET).

Thank you for your understanding.

Your VDRC Team

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End of year ordering/shipping schedule (Nov 17, 2020)

Dear VDRC users,

This year we will be closed for shipping from 19th December 2020 until 6th January 2021. Past experience has shown that this is a poor time to ship stocks due to the cold weather, increased postal traffic and holiday closings. Please plan your orders accordingly.

The ordering deadline for guaranteed shipping before Christmas is 29th Nov, midnight CET, for small orders (300 items or less).

The last shipping date for 2020 will be 13th Dec for deliveries to countries outside the EU and 18th Dec within the EU.

Large orders and any orders placed after 29th Nov will be processed as soon as possible, but with no guarantee that they can be dispatched by 18th Dec.

Any orders not dispatched by 18th Dec will be put on hold until we begin shipping again on 7th Jan 2021. The website will be closed for ordering on 30th and 31st Dec 2020.

We would like to thank you for your co-operation and custom throughout the whole year and wish you a happy festive time.

Your VDRC Team

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New resource: Fly Extract is available to order (Jul 15, 2020)

Dear VDRC users,

Fly Extract, from OregonR adults, is an essential component for culturing of many insect cell lines derived from ovaries or imaginal discs.

The VDRC has been providing Fly Extract for a number of Vienna Biocenter research groups and now extends this service to the Drosophila community. The VDRC Fly Extract is produced using a protocol developed by the lab of Julius Brennecke (IMBA, Vienna), which has been successfully growing OSC cells using this extract since 2010 (Sienski et al., Cell 2012).

If you would like to use VDRC Fly Extract for your cell lines, see Fly Extract for further details on recommended usage conditions for specific cell lines, as well as ordering, payment and shipping instructions.

For any questions or help, please contact us: office@vdrc.at

Your VDRC Team

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Update regarding VDRC shipping operations (May 10, 2020)

Dear VDRC users,

Whilst abiding by the COVID-19 lockdown and social distancing rules to ensure the safety of our staff, the VDRC team is continuing to work in shifts to ensure all our fly stocks are healthy. Stock maintenance is still our highest priority, but we are now able to take a further step towards normality by ramping up our shipping operations.

What changed?
From now on we are resuming our pre-COVID system of processing orders immediately they are received and shipping them as soon as possible. We still cannot guarantee shipment within 2 weeks but will do everything possible to minimize the turnaround time.

By default, we will ship your order as soon as we have made it ready, however, we appreciate that not everyone is in the fortunate situation of being able to receive their order. If you place an order but wish it to be kept on hold for shipment at a later date, please let us know by contacting office@vdrc.at.

If there are any changes we will update you via the news section of our website (www.vdrc.at) and twitter (@VDRC_flies).

For any questions or help, please contact us: office@vdrc.at

Your VDRC Team

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Shipping operations resumed (Apr 07, 2020)

Dear VDRC users,

Due to COVID-19 lockdown measures, the VDRC team has had to make some operational changes, but the good news is that we have continued maintaining our full stock collection, so all our stock IDs are available for ordering.

Stock maintenance will continue to be our highest priority, but we are pleased to inform you that we are now able to start shipping again. This means that you can continue placing orders via our website as normal and they will be processed as soon as possible. We’ll do our best to minimize the turnaround time, but it is currently not possible to guarantee shipment within 2 weeks.

New orders
Once your order has been placed, please get in touch with us to discuss whether you are able to receive deliveries or whether your order should be put on hold. If we do not get confirmation from you that shipping can go ahead, your order will remain on hold.
Pre-existing orders
For pre-existing orders that are currently on hold, please contact us if you would like us to proceed with shipping, otherwise your order will remain on hold until the situation changes.

We appreciate your patience and understanding and if you have any questions, please contact us: office@vdrc.at

If there are any changes we will update you via the news section of our website (www.vdrc.at) and twitter (@VDRC_flies).

Your VDRC Team

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COVID-19 emergency update (Mar 13, 2020)

Dear VDRC users,

Due to reasons beyond our control relating to COVID-19 containment measures (customs closing, cancelled flights etc.) we regret to inform you that we will be unable to continue with our full service at the current time. This means that we will be unable to uphold our guarantee of shipping orders within 2 weeks and will not be able to refund you if your package is delayed. All orders that have already been prepared and packaged will be sent as soon as possible. Rest assured that any new orders you place will be kept on hold in our database and will be prepared and shipped as soon as the situation improves.

We are sure you appreciate that this is an emergency situation and thank you for your understanding.

If you have any questions, please feel free to contact us contact us (office@vdrc.at).

Your VDRC Team

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Shipping update regarding coronavirus (Feb 28, 2020)

Dear VDRC users,

Due to the spread of COVID-19, some destinations may not be able to receive deliveries by Fedex or DHL. To avoid that we send your package and it doesn’t get through, we ask that you please keep an eye on the situation in your area inform us straight away if you will be unable to receive your package. In these cases we will be happy to hold on to your order and send it once you inform us that the restrictions have been lifted and delivery can proceed as normal.

Your VDRC Team

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Sub-library lists of RNAi lines (GD, KK, shRNA) (Dec 02, 2020)

Dear VDRC users,

For ease of ordering of defined, focused sub-libraries, we have created many sub-library lists of RNAi lines (GD, KK, shRNA).

The 'RNAi Sub-library' section includes the following lists:

  • human related genes (e.g.human gene orthologs sub-library, human disease-related orthologs sub-library)
  • genes associated with specific signaling pathways (e.g. JAK-STAT, Notch and Toll signaling pathways)
  • genes associated by biochemical and/or biological function (e.g. transcription factor genes, RNA binding genes, ubiquitin-related genes).

By clicking on each sub-library, the list of available lines for the associated genes will be displayed, enabling you to “add all to cart” or to select a subset.

Your VDRC Team

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End of year ordering/shipping schedule (Nov 11, 2019)

Dear VDRC users,

This year we will be closed for shipping from 18th December 2019 until 6th January 2020. Past experience has shown that this is a poor time to ship stocks due to the cold weather, increased postal traffic and holiday closings. Please plan your orders accordingly.

The ordering deadline for guaranteed shipping before Christmas is 2nd Dec, midnight CET, for small orders (300 items or less). The last shipping date for 2019 will be 16th Dec. Large orders and any orders placed after 2nd Dec will be processed as soon as possible, but with no guarantee that they can be dispatched by 16th Dec.

Any orders not dispatched by 16th Dec will be put on hold until we begin shipping again on 7th Jan 2020. The website will be closed for ordering on 30th and 31st Dec 2019.

We would like to thank you for your co-operation and custom throughout the whole year and wish you a happy festive time.

Your VDRC Team

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New lines added - Heidelberg CFD CRISPR library (Sep 04, 2019)

We are very pleased to announce that The Heidelberg CFD CRISPR Library, generated by the laboratory of Michael Boutros at the German Cancer Research Center (DKFZ) and Heidelberg University, has been donated to the VDRC for distribution.

These lines enable loss-of-function mutations in essential or non-essential genes in a germline restricted, ubiquitous or tissue specific fashion:

  • ~1600 sgRNA lines primarily targeting:
    • kinases, phosphatases and transcription factors
    • some fly orthologs of genes implicated in human pathologies
  • 20 toolkit stocks
    • UAS-Cas9 lines with a range of expression levels
    • UAS-Cas9 combined with common Gal4 driver lines
    • Lines for induction of Cas9 expression by FLP-out

For further details see here.

Full details about the lines can be found in the following Biorxiv preprint: A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila, Port et al (2019). See also https://www.crisprflydesign.org Lines will be available in batches as soon as possible.

The full list of expected lines is here:

  • HD CFD sgRNA
  • HD CFDtools

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New price scheme - as of 4th September 2019 (Sep 04, 2019)

The Vienna Drosophila Resource Center (VDRC) is part of the Vienna Biocenter Core Facilities (VBCF), a non-profit research company, publicly funded by the Austrian Federal Ministry of Education, Science and Research, and the City of Vienna via the Vienna Business Agency.

Up until now, fees for use of the resources have provided approximately 50% of the cost of VDRC services with the remaining 50% coming from VBCF funding. However, since Austria currently represents less than 2% of the total VDRC usage, (with US ~40%, Europe ~40% and Asia ~15%) we are required to increase the proportion of our running costs coming from user fees.

To achieve this, we will be implementing a new price scheme as of 4th September 2019 [see here for details].

The good news is that the fees for orders of 6 stocks or less have actually been reduced. When ordering 7 lines (the median number of lines ordered by VDRC customers last year), we have increased the price by 2%.
To offset the slightly increased price for larger orders, we have improved our service to guarantee that all orders up to 300 lines (previously 100) will qualify for fast shipment and will be dispatched within 2 weeks. This means that the total cost of your order may still be cheaper than before.

Examples

Number of items Old price
(€ total)
New price
(€ total)
Price difference
new - old €
% difference
new - old
1 77.80 70 -7.80 -10%
7 353.40 360 +6.60 +2%
200 2x 1.832 = 3.664 1x 2.815 -849 -23%

We would like to emphasize that your costs are still being subsidized by Austrian grant funding and you are not being asked to cover the full cost.

We appreciate your understanding of the situation and hope that you will continue to use the VDRC services, thereby helping to make it a sustainable resource for the future.

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Stock Pruning List, RNAi lines (GD and KK libraries) - order by 15th Sep 2019 (Aug 15, 2019)

Dear VDRC users,

In order to streamline the VDRC stock collection we will be discarding nearly 3500 RNAi lines (3339 GDs and 122 KKs) [list].

We aim to keep 2 independent lines per target gene, each line with a different construct and different target sequence. We have prioritised keeping lines with least off targets. After pruning there will still be at least 2 remaining RNAi lines (GD, KK or shRNA) targeting the same CG as the discarded line.

Please check the list carefully and ensure that you order the lines you need for current or future experiments. These stocks will no longer be available for ordering after Sep 15th 2019, so be sure to order in good time - they will be gone forever after this date!

Your VDRC Team

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Stock Pruning List, VT GAL4 - order by Sep 30th 2019 (Aug 07, 2019)

Dear VDRC users,

In order to streamline the VDRC stock collection to reflect actual usage by the community and to make way for new stocks, we will be discarding a large subset of our Vienna Tiles (VT) GAL4 library [list].

These stocks will no longer be available for ordering after Sep 30th 2019, so if you need them, please order in good time - they will be gone forever after this date!

Your VDRC Team

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General price increase (Dec 20, 2018)

Dear VDRC users,

VDRC would like to inform you about our general price increase effective January 1, 2019. This is the first increase since 2014 and reflects increased costs due to inflation.

VDRC is a non-profit research organization and our running costs and thus your fees are heavily subsidized. Currently ~50% of the total running costs are funded by a grant from the Austrian Federal Ministry for Science and Research and the city of Vienna. The remaining costs must be recovered from user fees. We hope you understand that the price increase is necessary to ensure that we continue to reach this target, thus securing the longer term availability of our collection for the community.

See [here] for new prices.

Your VDRC Team

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End of year ordering/shipping schedule (Nov 5, 2018)

Dear VDRC users,

This year we will be closed for shipping from 18th December 2018 until 6th January 2019. Past experience has shown that this is a poor time to ship stocks due to the cold weather, increased postal traffic and holiday closings. Please plan your orders accordingly.

The ordering deadline for guaranteed shipping before Christmas is 3rd Dec, midnight CET, for small orders (100 items or less). The last shipping date for 2018 will be 17th Dec. Large orders and any orders placed after 3rd Dec will be processed as soon as possible, but with no guarantee that they can be dispatched by 17th Dec.

Any orders not dispatched by 17th Dec will be put on hold until we begin shipping again on 7th Jan 2019. The website will be closed for ordering on 31st Dec 2018 and 1st Jan 2019.

We would like to thank you for your co-operation and custom throughout the whole year and wish you a happy festive time.

Your VDRC Team

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New stocks added from Ameres lab (Mar 06, 2018)

Dear VDRC users,

The group of Stefan Ameres (IMBA, Vienna) has donated several new stocks to the VDRC. Included are stocks which can be used as a tool in a groundbreaking technique called "mime-seq". Mime-seq enables Gal4-driven access to the miRNA repertoire of specific tissues and cell-types in flies. The method therefore enables researchers to profile microRNAs in their endogenous context at cellular resolution - a level of specificity and sensitivity which was previously not possible.

Details of the "mime-seq" method and associated fly stocks are published here:
Alberti, C., et al. (2018): "Cell-type specific sequencing of microRNAs from complex animal tissues." Nature Methods. doi: 10.1038/nmeth.4610 For ordering, all stocks from the Ameres lab can be found under "S. Ameres stocks" in the Other Resources section.

VDRC is open to donations of highly used stocks for integration into its community stock center collection. In addition, we offer a Private Stock Keeping Service where we will maintain and distribute your personal fly stock/plasmid collection on your behalf.
See the Policy for VDRC Stock Keeping Services section for more information.

If you wish to donate resources to VDRC or use our Private Stock Keeping Service, please contact us (office@vdrc.at) to discuss as early as possible.

Your VDRC Team

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Import regulation for US and Canada (Dec 22, 2017)

Dear VDRC users,

As of March 21, 2017, import regulations for the US and Canada have been amended regarding the "TSCA certification". From now on the TSCA must be signed by the Importer (VDRC user). Next time you place an order you will receive an automatic email notification with an attached TSCA which you have to fill out, sign and send back to us.
We will include this document with each shipment to the US and Canada.

For further information please see:
https://www.epa.gov/tsca-import-export-requirements/tsca-requirements-importing-chemicals

If you have any questions, please feel free to contact us contact us (office@vdrc.at).

Your VDRC Team

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End of year ordering/shipping schedule (Nov 2, 2017)

Dear VDRC users,

This year we will be closed for shipping from 19th December 2017 until 8th January 2018. Past experience has shown that this is a poor time to ship stocks due to the cold weather, increased postal traffic and holiday closings. Please plan your orders accordingly.

The ordering deadline for guaranteed shipping before Christmas is 3rd Dec, midnight CET, for small orders (100 items or less). The last shipping date for 2017 will be 18th Dec. Large orders and any orders placed after 3rd Dec will be processed as soon as possible, but with no guarantee that they can be dispatched by 18th Dec.

Any orders not dispatched by 18th Dec will be put on hold until we begin shipping again on 8th Jan 2018. The website will be closed for ordering on 30th and 31st Dec 2017 and 1st Jan 2018.

We would like to thank you for your co-operation and custom throughout the whole year and wish you a happy festive time.

Your VDRC Team

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Further shRNA lines available (Sep 18, 2017)

Dear VDRC users,

The VDRC is continuing to create new shRNA and we have recently added more lines to extend our RNAi our collection.
See RNAi Library for the full list.

Your VDRC Team

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25th European Drosophila Research Conference in London, Sep 22-25, 2017 (Sep 17, 2017)

Dear VDRC users,

The VDRC will be exhibiting at the 25th European Drosophila Research Conference in London.
You are welcome to visit us to find out about our latest innovations and give us your feedback.

We look forward to seeing you there!

Your VDRC Team

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Vienna Tiles (VT) GAL4 Stock Pruning List - order by 30th Sep 2017 (Jul 11, 2017)

Dear VDRC users,

To streamline the VDRC stock collection, we will continue to maintain only 1000 Vienna Tiles (VT) GAL4 stocks, including those most frequently requested and those with sparser expression patterns in the adult brain.
The remaining ~7500 low-use VT GAL4 stocks will be discarded [list]. These will no longer be available for ordering after Sep 30th 2017, so if you need them, please order in good time - they will be gone forever after this date!

Your VDRC Team

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57th Annual Drosophila Research Conference in San Diego, March 29 - April 2, 2017 (Mar 20, 2017)

Dear VDRC users,

The VDRC is happy to attend the 57th Drosophila Research Conference in San Diego.
You will find us at booth # 214. You are welcome to visit us to find out about our latest innovations and give us your feedback.

We look forward to seeing you there!

Your VDRC Team

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"NEW" and "SIMILAR" tags added in search results (Jan 25, 2017)

We have made some changes to the way search results are displayed:

We've added the tag "NEW" to resources which have been recently added to the VDRC collection, to help you clearly distinguish them in the search results table.

The tag "SIMILAR" will appear when you search for a specific term and we wish to show you related resources. As an example, with the search term "33277" the search results will display the primary hit first (VDRC_ID 33277) and below it all related lines with the tag "SIMILAR", in this case 2 further resources matching the same CG number. If the search is more general e.g. with the search term "*10125", there can be more than one primary result from the search. In such a case, one primary result and its SIMILAR lines will be listed first, followed by the next primary result and its SIMILAR lines, with each related group separated by a solid line. Currently it is not possible to sort the SIMILAR lines, nor to filter them by library type, but we're working on it.

If the results are too confusing, we would suggest trying again with a more specific search term!

We would welcome your feedback on these changes. Please send any comments to office@vdrc.at.

Your VDRC Team

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VDRC website relaunch (Dec 15, 2016)

Dear VDRC users,

We have modernised our homepage (www.vdrc.at), not only to give it a fresh look, but also to make it even more user-friendly and to incorporate some new features.

These include:

  • Highlighting the most recently added resources
  • A regularly updated list of the most popular lines
  • Addition of links to FlyBase Reference Reports showing when the use of a specific line has been cited in publications
  • Improved search features
  • Ability to store lines in the shopping cart when you log out
  • Responsive web design for ease of use on desktops, tablets and phones

We would welcome your feedback and ideas for improvement and please do not hesitate to contact us if you find anything that does not work as it should.

Our thanks go to Barbara Wohlmuth and Thomas Micheler (Strategic Information Management Facility, VBCF) for realizing this project.

Your VDRC Team

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End of year shipping schedules (Nov 10, 2016)

Dear VDRC users,

This year we will be closed for shipping from 17th December 2016 until 9th January 2017. Past experience has shown that this is a poor time to ship stocks due to the cold weather, increased postal traffic and holiday closings. Please plan your orders accordingly.

The ordering deadline for guaranteed shipping before Christmas is 1st Dec, midnight CET, for small orders (100 items or less). The last shipping date for 2016 will be 16th Dec. Large orders and any orders placed after 1st Dec will be processed as soon as possible, but with no guarantee that they can be dispatched by 16th Dec.

Any orders not dispatched by 16th Dec will be put on hold until we begin shipping again on 9th Jan 2017. The website will be closed for ordering on 30th and 31st Dec 2016 and 1st Jan 2017.

We would like to thank you for your co-operation and custom throughout the whole year and wish you a happy festive time.

Your VDRC Team

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VDRC stockcenter offline 14.10.2016 to 17.10.2016 (Oct 11, 2016)

Dear VDRC users,

Due to moving of our central server infrastructure, placing orders will not be possible on Fri 14th October from 9:00 CET. We expect to be up and running again on Mon 17th Oct.
Thank you for your understanding.

We apologise for the inconvenience and thank you for your patience and understanding.

Your VDRC Team

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Potential payment problems (June 22, 2016)

Dear VDRC users,

Due to an issue with the SIX Payment System, which is beyond the control of the VDRC, you may be experiencing problems with ordering (https://www.six-payment-services.com/en/home.html#country=at). The SIX team ensure us that they are working on it urgently and hope to fix the problem as soon as possible. If your order fails, please try again later.

We apologise for the inconvenience and thank you for your patience and understanding.

Your VDRC Team

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New stocks added from Wasser lab (May 18, 2016)

Dear VDRC users,

Several lines from the private collection of Martin Wasser (Bioinformatics Institute, Singapore) are now publicly available through VDRC.

The collection consists of 15 lines which can be displayed by using the search term "wasser" or under "Browse the M. Wasser Stocks (MW-STOCK)" in the "Other Resources" section and includes a variety of mutant alleles, tagged constructs and reporters lines from the following publications:

Wasser M, Chia W. (2000)
The EAST protein of drosophila controls an expandable nuclear endoskeleton.
Nat Cell Biol. 2000 May;2(5):268-75.
PubMed 10806477

Chinta R and Wasser M (2012)
Three-dimensional segmentation of nuclei and mitotic chromosomes for the study of cell divisions in live Drosophila embryos.
Cytometry A. 2012 Jan;81(1):52-64. doi: 10.1002/cyto.a.21164. Epub 2011 Nov 8.
PubMed 22069299

Puah WC and Wasser M (2016)
Live imaging of muscles in Drosophila metamorphosis: Towards high-throughput gene identification and function analysis.
Methods. 2016 Mar 1;96:103-17. doi: 10.1016/j.ymeth.2015.09.028. Epub 2015 Oct 1.
PubMed 26431669

Kuleesha Y, Puah WC, Wasser M (2016)
A model of muscle atrophy based on live microscopy of muscle remodelling in Drosophila metamorphosis.
R Soc Open Sci. 2016 Feb 10;3(2):150517. doi: 10.1098/rsos.150517. eCollection 2016 Feb.
PubMed 26998322

When using these lines, please cite the appropriate Wasser publication and acknowledge the VDRC for providing the lines.

Your VDRC Team

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New stocks added from Harvey lab (May 11, 2016)

Dear VDRC users,

Control lines for the KK library, donated by Kieran Harvey (Peter MacCallum Cancer Centre, Melbourne, Australia) are now available. (For details see Vissers et al, Nat. Comm. (2016) : A Drosophila RNAi library modulates Hippo pathway-dependent tissue growth).

The collection consists of 5 lines which can be displayed by using the search term "harvey":

An RNAi-toolkit stock (VDRC_ID 60101) where the landing sites at 40D and 30B in the KK library host strain have been separated by meiotic recombination. This line contains Gal4-responsive UAS repeats but no functional RNAi coding sequence at 40D and no transgene insertion at 30B and enables researchers to easily test whether their genetic screen of interest will be affected by ectopic tiptop expression.

4 further KK lines were created by meiotic recombination to separate the insertions at 30B and 40D. These lines contain an insertion of the UAS-RNAi construct in the landing site at 30B only and no insertion at the 40D landing site.
VDRC_ID 111000 is the "30D only" version of VDRC_ID 107151 (CG8208, MBD-like)
VDRC_ID 111001 is the "30D only" version of VDRC_ID 104523 (CG4005, Yki)
VDRC_ID 111002 is the "30D only" version of VDRC_ID 106174 (CG12072, Wts)
VDRC_ID 111003 is the "30D only" version of VDRC_ID 105838 (CG4236, Caf1)

When using these lines, please reference Vissers et al (2016) and acknowledge the VDRC for providing the lines.

Your VDRC Team

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RNAi collection extended – new shRNA lines added (Apr. 18, 2016)

Dear VDRC users,

The Vienna Drosophila Resource Center is pleased to announce a collection of new UAS-RNAi lines using short hairpin microRNA (shRNA) technology to extend and complement the current VDRC RNAi collection. Nearly 200 new lines are already available (www.vdrc.at) and a further 300 lines, currently in the VDRC production pipeline, will be made available to the community as soon as they are ready.

For commonly studied genes, where there is only 1 RNAi line in the VDRC GD or KK collection at present, we aim to add a further functional RNAi line to facilitate verification of phenotypes.

We have used shRNA technology to create these lines, as used extensively by the Transgenic RNAi Project (TRiP) and have collaborated with the TRiP team for hairpin design. The VDRC shRNA lines are consistent with, and complementary to, the TRiP shRNA lines, but the shRNAs target mRNA sequences which are independent of all current resources. The new collection therefore extends the range of RNAi lines available to the Drosophila research community.

For further details, see here.

Your VDRC Team

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New stocks added from Brennecke group (Feb. 18, 2016)

Dear VDRC users,

Our collection of "Other Resources" is growing and we have now added 175 stocks provided by Julius Brennecke (IMBA, Vienna). The new collection contains a variety of published stocks including 60 RNAi lines plus mutant alleles, tagged constructs, reporters, piRNA biogenesis reporters, miRNA sensors and tethering lines.

VDRC is open to donations of highly used stocks for integration into its community stock center collection. In addition, we offer a Private Stock Keeping Service where we will maintain and distribute your personal fly stock/plasmid collection on your behalf. See the Policy for VDRC Stock Keeping Services section for more information.

If you wish to donate resources to VDRC or use our Private Stock Keeping Service, please contact us (office@vdrc.at) to discuss as early as possible.

Your VDRC Team

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KK landing site update (Jan. 14, 2016)

Dear VDRC users,

The Vienna Drosophila Resource Center (VDRC) would like to inform you of a recent publication regarding the KK RNAi library and a new stock for control experiments: KK Library Reliability

Your VDRC Team

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VDRC host institute name change (Jan. 01, 2016)

Dear VDRC users,

As of 1st Jan 2016, the VDRC host institute will change its name from "Campus Science Support Facilities GmbH" (CSF) to "Vienna Biocenter Core Facilities GmbH" (VBCF).

All VDRC services will continue exactly as before, with the only change being that invoices will be issued by VBCF. All bank details remain unchanged.

Your VDRC Team

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