349903
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SKU
DD-IM-349903
| VDRC Id | 349903 |
|---|---|
| Library | DD-Im |
| Sub-Category | mutants |
| Status | available |
| Comment | BL4. NimC1-delta and Eater-delta mutations were generated by homologous recombination (both genes are replaced by a w+ cassette), isogenized in the w[1118] DrosDel genetic background. NimC1-delta, Eater-delta have strongly reduced phagocytosis ability and defective hemocyte sessility due to the absence of Eater. While NimC1-delta, Eater-delta larvae have more hemocytes, NimC1-delta, Eater-delta adults tend to have decreased hemocyte number over time. This line can be used to assess the function of phagocytosis, although it likely impacts other processes. |
| Construct Id | 349903 |
| Genotype | w[1118]; NimC1[Delta]; eater[Delta] |
| Gene Symbol | NimC1 |
| Gene Name | Nimrod C1 |
| Synonyms | BG:DS00180.10 CG6124 CT25688 DrosDel Immunity panel Nim NimC NimC1 Nimrod C1 NimrodC1 P1 eater nimC1 nimrod nimrod C1 nimrodC1 |
| Keywords | DrosDel Immunity panel |
| Inserted Chromosome | 2;3 |
| Viability | viable |
| Publication | Bretscher et al., Biol Open (2015) |
| Provider Scientist | Bruno Lemaitre with the help of Mark Hanson |
| Provider Organization | EPFL |