349902
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SKU
DD-IM-349902
| VDRC Id | 349902 |
|---|---|
| Library | DD-Im |
| Sub-Category | mutants |
| Status | available |
| Comment | BL3. PPO1-delta and PPO2-delta mutations were generated by homologous recombination (homologous replacement of PPO1 sequences with w[+]), isogenized in the w[1118] DrosDel genetic background. PPO1-Delta, PPO2-delta show no hemolymphatic melanization after injury. PPO3 in lamellocytes can still contribute to melanization around wasp eggs (Dudzic et al, BMC Biol 2015) |
| Construct Id | 349902 |
| Genotype | w[1118]; PPO1[Delta], PPO2[Delta] |
| Gene Symbol | PPO1 |
| Gene Name | Prophenoloxidase 1 |
| FlyBase gene number | FBgn0000165 FBgn0003081 FBgn0004627 FBgn0261362 FBgn0261382 FBgn0283437 |
| CG Number (r6.01) | CG42639 |
| Synonyms | A1 A[[1]] Bc Black Cell CG5779 CG8193 Diphenol oxidase A1 subunit DmPPO1 DmePPOA1 Dox-A1 DoxA1 DrosDel Immunity panel Monophenol oxidase Monophenoloxidase Mox PO PO A1 PO54 PPO PPO-1 PPO-A1 PP |
| Keywords | DrosDel Immunity panel |
| Inserted Chromosome | 2 |
| Viability | viable |
| Publication | Binggeli et al., PLoS Pathog (2014) |
| Provider Scientist | Bruno Lemaitre with the help of Mark Hanson |
| Provider Organization | EPFL |