349901
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SKU
DD-IM-349901
| VDRC Id | 349901 |
|---|---|
| Library | DD-Im |
| Sub-Category | mutants |
| Status | available |
| Comment | BL2. spz[rm7] or spz[4] is a genetically null mutation in spz (generated by EMS during Nusslein-Volhard and Wieschaus screen). Several markers of the original stock (M317 Tubingen stock center) including ebony were removed by recombination (Lemaitre et al., Cell 1996). spz[rm7] are homozygous viable, female sterile. This mutation blocks the activation of the Toll pathway. Note that the Toll pathway might be activated independently of spz by spz[5] (Nonaka et al., Biochem Biophys Res Comm 2018)). |
| Construct Id | 349901 |
| Genotype | w[1118]; ; spz[rm7]/TM6C, Sb[1] |
| Gene Symbol | spz |
| Gene Name | spatzle |
| Synonyms | CT19282 DrosDel Immunity panel Protein spaetzle precursor SPZ Spaetzle Spatzle Spatzle-1 Spz Spz-1 Spz1 mel(3)7 spaetzle spatzle spazle spaztle spz |
| Keywords | DrosDel Immunity panel |
| Inserted Chromosome | 3 |
| Viability | sterile |
| Publication | Morisato & Anderson, Cell (1994) |
| Provider Scientist | Bruno Lemaitre with the help of Mark Hanson |
| Provider Organization | EPFL |