DrosDel Immunity Panel
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| Name | VDRC Id | Library | Sub-Category | Genotype | Comment | Construct Id | Publication | Provider Scientist | Provider Organization | Gene Symbol | FlyBase gene number | Synonyms | Sequence | RRID | Comment | Gene Name | Keywords | Price (net) | Add to Cart | ||
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| 349912 |
349912
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DD-Im
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mutants
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w[1118]; Def[SK3], AttC[Mi], Dro-AttAB[SK2], Mtk[R1], Dpt[SK1]/CyO; Drs[R1], AttD[SK1], CecA-C[Delta]/TM6C, Sb[1]
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BL13. DeltaAMP14: 8 deletions removing 14 Antimicrobial peptides genes (AMP10 + deletion of Cecropin locus), all isogenized in the w[1118] DrosDel genetic background. DroAtt removes Drosocin locus (2 peptides (Hanson et al., 2022)) and Attacin A and B. The MtkR1 and DrsR1 loci each carry one w+ transgene, and the AttCMi mutation also causes GFP to be expressed in the eyes, ocelli, and occasionally the gut. The CecA-C mutation also produces DsRed in the eyes, ocelli, and abdomen. Balancers floating: CyO; TM6C, Sb (not Tubby).
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349912
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Bruno Lemaitre with the help of Mark Hanson
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EPFL
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AttA
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143607_at
AHA ATT ATTA Att Att A Att-A AttA AttC AttD AttaA Attacin Attacin A Attacin-A Attacin-A precursor Attacin-A AttacinA AttacinA Attackin BcDNA:LP05763 CecA-C DEF DIM 26 Def Defe |
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BL13. DeltaAMP14: 8 deletions removing 14 Antimicrobial peptides genes (AMP10 + deletion of Cecropin locus), all isogenized in the w[1118] DrosDel genetic background. DroAtt removes Drosocin locus (2 peptides (Hanson et al., 2022)) and Attacin A and B. The MtkR1 and DrsR1 loci each carry one w+ transgene, and the AttCMi mutation also causes GFP to be expressed in the eyes, ocelli, and occasionally the gut. The CecA-C mutation also produces DsRed in the eyes, ocelli, and abdomen. Balancers floating: CyO; TM6C, Sb (not Tubby).
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Attacin-A
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DrosDel Immunity panel
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| 349913 |
349913
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DD-Im
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mutants
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w[1118]; Def[SK3]; Df(3R)CecA-C[Delta]/TM6, Sb[1]
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BL14. DeltaAMP Group A: 2 deletions removing the Defensin and the Cecropin Locus (4 genes), all isogenized in the w[1118] DrosDel genetic background. The polymorphism at the Bulletin locus is Alanine.
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349913
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Bruno Lemaitre with the help of Mark Hanson
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EPFL
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Def
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143607_at
CecA-C DEF DIM 26 Def Defencin Defensin Defensin precursor Definsin DeltaAMP Group A Dfn DrosDel Immunity panel def defensin |
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BL14. DeltaAMP Group A: 2 deletions removing the Defensin and the Cecropin Locus (4 genes), all isogenized in the w[1118] DrosDel genetic background. The polymorphism at the Bulletin locus is Alanine.
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Defensin
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DrosDel Immunity panel
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| 349914 |
349914
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DD-Im
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mutants
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w[1118]; Mtk[R1]; Drs[R1]
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BL15. DeltaAMP Group C: 2 mutations removing 2 antifungal peptides (2 genes), all isogenized in the w[1118] DrosDel genetic background.
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349914
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Bruno Lemaitre with the help of Mark Hanson
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EPFL
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Mtk
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BcDNA:RH07954 DIM 17 DeltaAMP Group C DrosDel Immunity panel Drosophila Immune induced molecule 17 Drs METCH Mek Metc Metch Metchnikowin Metchnikowin A Metchnikowin B Metchnikowin precursor Metchnikowine Mtk |
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BL15. DeltaAMP Group C: 2 mutations removing 2 antifungal peptides (2 genes), all isogenized in the w[1118] DrosDel genetic background.
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Metchnikowin
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DrosDel Immunity panel
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| 349915 |
349915
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DD-Im
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mutants
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w[1118]; AttC[Mi], DroAtt[SK2], Dpt[SK1]; AttD[SK1]
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BL16. DeltaAMP Group B: 4 mutations removing the two Diptericin, the 4 Attacins and Drosocin, all isogenized in the w[1118] DrosDel genetic background. DroAtt removes the Drosocin locus (two peptides) and Attacin A and B (Hanson et al., 2022).
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349915
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Bruno Lemaitre with the help of Mark Hanson
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EPFL
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AttC
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Att
AttC AttD Attacin Attacin C Attacin-C Attacin-C precursor AttacinC Attackin C DIM 16 DIM-16 DeltaAMP Group B Dpt DroAtt DrosDel Immunity panel Drosophila Immune induced molecule 16 MPAC att att |
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BL16. DeltaAMP Group B: 4 mutations removing the two Diptericin, the 4 Attacins and Drosocin, all isogenized in the w[1118] DrosDel genetic background. DroAtt removes the Drosocin locus (two peptides) and Attacin A and B (Hanson et al., 2022).
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Attacin-C
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DrosDel Immunity panel
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| 349916 |
349916
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DD-Im
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mutants
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w[1118]; ; Df(3R)CecA-C[Delta]
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BL17. A deletion removing the Cecropin Locus (4 genes), all isogenized in the w[1118] DrosDel genetic background.
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349916
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Bruno Lemaitre with the help of Mark Hanson
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EPFL
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CecA1
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CEC
CG4740 Cec Cec A1 CecA CecA-C CecA1 CecA2 CecB CecC Cecropin Cecropin A Cecropin A1 Cecropin-A Cecropin-A1 Cecropin-A1/A2 precursor CecropinA CecropinA1 DrosDel Immunity panel cec cecA cec |
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BL17. A deletion removing the Cecropin Locus (4 genes), all isogenized in the w[1118] DrosDel genetic background.
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Cecropin A1
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DrosDel Immunity panel
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| 349917 |
349917
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DD-Im
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mutants
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w[1118]; ; AttD[SK1]
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BL18. A mutation affecting Attacin D, isogenized in the w[1118] DrosDel genetic background.
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349917
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Bruno Lemaitre with the help of Mark Hanson
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EPFL
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AttD
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Att
AttD Attacin Attacin D Attacin-D AttacinD Attackin DrosDel Immunity panel att att D attD attacin attacin D |
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BL18. A mutation affecting Attacin D, isogenized in the w[1118] DrosDel genetic background.
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Attacin-D
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DrosDel Immunity panel
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| 349918 |
349918
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DD-Im
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mutants
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w[1118]; Dro[SK4]
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BL19. A mutation affecting the whole Drosocin locus, isogenized in the w[1118] DrosDel genetic background.
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349918
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Bruno Lemaitre with the help of Mark Hanson
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EPFL
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Dro
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143609_at
AttA AttB BcDNA:RH31634 DIM 11 DIM 15 DIM 9 DIM-15 DROC Drc Dro Dro1 Dros DrosDel Immunity panel Drosocin Drosocin precursor Drosophila Immune induced molecule 11 Drosophila Immune induced molec |
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BL19. A mutation affecting the whole Drosocin locus, isogenized in the w[1118] DrosDel genetic background.
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Drosocin
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DrosDel Immunity panel
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| 349919 |
349919
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DD-Im
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mutants
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w[1118], Tsf1[JP94]
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BL20. A mutation affecting the Tsf1 gene, isogenized in the w[1118] DrosDel genetic background.
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349919
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Bruno Lemaitre with the help of Mark Hanson
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EPFL
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Tsf1
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143958_at
DTAF-transferrin DrosDel Immunity panel TSF1 Tf Transferrin Transferrin 1 Transferrin1 Trf Tsf1 anon-EST:Posey265 lincRNA.S9601 transferrin transferrin 1 transferrin precursor tsf1 |
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BL20. A mutation affecting the Tsf1 gene, isogenized in the w[1118] DrosDel genetic background.
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Transferrin 1
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DrosDel Immunity panel
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| 349920 |
349920
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DD-Im
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mutants
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w[1118]; BaraA[Delta]{dsRed}
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BL21. Complete deletion of BaramicinA locus, isogenized in the w[1118] DrosDel genetic background. This mutation retains the full gene region of CG30059, but replaces sequence directly downstream with a DsRed construct. Note that this genotype is lacking both CG18279 (BaraA1) and CG33470 (BaraA2), and also lacks CG18278 as the mutation was generated in a background that never had the BaraA1 + CG18278 locus duplication in the first place. i.e. generated in a background with only CG33470 and CG30059.
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349920
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Bruno Lemaitre with the help of Mark Hanson
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EPFL
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BaraA1
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BaraA
BaraA1 BaraA2 CG18278 CG18279 Daisho1 Daisho2 DrosDel Immunity panel Group D IM10 IM12 IM13 IM22 IM24 IM5 IM6 IM8 |
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BL21. Complete deletion of BaramicinA locus, isogenized in the w[1118] DrosDel genetic background. This mutation retains the full gene region of CG30059, but replaces sequence directly downstream with a DsRed construct. Note that this genotype is lacking both CG18279 (BaraA1) and CG33470 (BaraA2), and also lacks CG18278 as the mutation was generated in a background that never had the BaraA1 + CG18278 locus duplication in the first place. i.e. generated in a background with only CG33470 and CG30059.
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Baramicin A1
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DrosDel Immunity panel
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| 349921 |
349921
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DD-Im
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mutants
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w[1118]; DptA[Delta-822]
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BL22. A premature stop mutation affecting the DptA locus, derived from the strain DGRP-822, isogenized in the w[1118] DrosDel genetic background.
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349921
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Bruno Lemaitre with the help of Mark Hanson
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EPFL
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DptA
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143443_at
DIPT DPT Dep Dip Dipt DiptA Diptericin Diptericin A Diptericin precursor Diptericin-A DiptericinA Dpt DptA DptB DrosDel Immunity panel dip dipt diptericin diptericin A dpt |
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BL22. A premature stop mutation affecting the DptA locus, derived from the strain DGRP-822, isogenized in the w[1118] DrosDel genetic background.
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Diptericin A
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DrosDel Immunity panel
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| 349922 |
349922
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DD-Im
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mutants
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w[1118]; DptB[KO]
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BL23. Deletion of the DptB locus (Barajas-Azpeleta, PLOS Gen, 2018), isogenized in the w[1118] DrosDel genetic background. This line induces the related gene DptA to a lesser extent compared to the DrosDel background, and so within this immune mutant panel, it may most accurately be considered a hypomorph for DptA alongside being fully null for DptB.
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349922
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Bruno Lemaitre with the help of Mark Hanson
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EPFL
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DptB
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147473_at
BcDNA:RH29451 DiptB Diptercin B Diptericin Diptericin B Diptericin-B DiptericinB Dpt DptB DrosDel Immunity panel diptericin B diptericin-like protein diptericin-like proteinm dpt B dptB dptlp |
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BL23. Deletion of the DptB locus (Barajas-Azpeleta, PLOS Gen, 2018), isogenized in the w[1118] DrosDel genetic background. This line induces the related gene DptA to a lesser extent compared to the DrosDel background, and so within this immune mutant panel, it may most accurately be considered a hypomorph for DptA alongside being fully null for DptB.
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Diptericin B
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DrosDel Immunity panel
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| 349923 |
349923
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DD-Im
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mutants
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w[1118]; DptA[S69R-4]
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BL24. Serine-arginine polymorphism at residue 69 of DptA (derived from DGRP-38), isogenized in the w[1118] DrosDel genetic background.
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349923
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Bruno Lemaitre with the help of Mark Hanson
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EPFL
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DptA
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143443_at
DIPT DPT Dep Dip Dipt DiptA Diptericin Diptericin A Diptericin precursor Diptericin-A DiptericinA Dpt DptA DptB DrosDel Immunity panel dip dipt diptericin diptericin A dpt |
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BL24. Serine-arginine polymorphism at residue 69 of DptA (derived from DGRP-38), isogenized in the w[1118] DrosDel genetic background.
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Diptericin A
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DrosDel Immunity panel
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